- 【SCI通讯】Mesomeric configuration makes polyleucine micelle an optimal nanocarrier
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- 所属单位:化学工程学院
- 发表刊物:Biomaterials Science
- 项目来源:国家自然科学基金项目
- 摘要:Micelle with mesomeric polyleucine (PDLLeu) core demonstrated the most uniform morphology, the smallest diameter and the highest drug loading capability compared to those with dextrorotatory (PDLeu), levorotatory (PLLeu) and racemic PLeu (PD/LLeu) cores. In addition, the modification with c(RGDfC) endowed the optimal PDLLeu micelle with enhanced intracellular drug release and cytotoxicity, indicating its great potential for targeted drug delivery.
- 第一作者:杨亚楠
- 论文类型:期刊论文
- 页面范围:1
- 是否译文:否
- 发表时间:2016-02-01