- [SCI通讯]Synthesis of PCL‐branched P(MMA‐co‐HEMA) to toughen electrospun PLLA fiber membrane
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- 所属单位：化学工程学院
- 发表刊物：Polymers for Advanced Technologies
- 项目来源：省、市、自治区科技项目
- 关键字：electrospinning, PCL‐branched P(MMA‐co‐HEMA), PLLA, toughness
- 摘要：Electrospun biodegradable fiber mesh is a promising alternative scaffold for delivering progenitor cells for repairing damaged or diseased tissue, but its cripple mechanical stability has not met the requirement of tissue engineering yet. In this work, the well‐defined poly(ε‐caprolactone)-branched poly(methyl methacrylate‐co‐hydroxyethylmethacrylate) (PCL‐PMH) has been successfully synthesized to toughen electrospun poly(L‐lactide) (PLLA) fiber membrane. Characterization of the obtained nanofibrous meshes indicates that PCL‐PMH and PLLA can be well blended to make smooth fibers, and fibrous diameter vary little with blending PCL‐PMH. The aggregation state of two macromolecules is closely correlated with blend ratio, molecular structure, and molecular weight of PCL‐PMH, and only when PCL‐PMH and PLLA form good interfacial adhesion can PMH give full play to its potential for toughening the fiber membrane. The tensile strength and elongation at break of the blend are 6.20 MPa and 63.40% under the optimal conditions, respectively, and it also exhibits the representative feature of toughness materials. The blending fiber membrane is as no cytotoxic as original PLLA. This work will provide a new way for toughness of electrospun fiber membrane in practice.
- 第一作者：宋晓峰
- 论文类型：期刊论文
- 卷号：29
- 页面范围：1
- 是否译文：否
- 发表时间：2018-01-01
