所属单位：化学与生命科学学院
教研室：食品教研室
发表刊物：Journal of Pharmaceutical and Biomedical Analysis
项目来源：省、市、自治区科技项目
摘要：Ionic liquid-based salt-induced liquid-liquid extraction was developed for the first time and applied tothe extraction of four active constituents, including polydatin, resveratrol, emodin, and physcion in Poly-gonum cuspidatum (P. cuspidatum). In this study, ionic liquid was used as extraction solvent. The dried P.cuspidatum samples purchased from the pharmacy were triturated and passed through a 120-mesh sieve.The obtained sample powders were dried to constant weight at 55◦, and then mixed with extraction sol-vent. The extraction was carried out with the aid of ultrasound. Three phases, including ionic liquid-rich,salt-rich and solid sample phases were formed in the presence of salt. The target analytes were enrichedin ionic liquid phase and then determined by high performance liquid chromatography. The experimen-tal parameters, such as type and volume of ionic liquid, type and amount of salt, pH value of extractionmedium, ultrasound power, ultrasound time and centrifugal condition, were optimized. The calibrationcurves showed good linear relationship (r > 0.9994). The limits of detection and quantification were in therange of 2.8–29.5 and 9.4–98.3 ng mL−1, respectively. The spiked recoveries were between 92.16% and105.41%. Compared with hot reflux extraction and ultrasound-assisted extraction, the proposed methodrequires less extraction solvent and time. The present method can be applied to the determination ofpolyphenols and anthraquinones in P. cuspidatum.
合写作者：王家琳,冯吉,徐璐,马金鹏,李吉龙,马睿,孙坤,张寒琦,王志兵
第一作者：王志兵
论文类型：期刊论文
卷号：163
页面范围：2
是否译文：否
发表时间：2019-01-30