songxiaofeng
|
- Supervisor of Doctorate Candidates
- Supervisor of Master's Candidates
- Name (Pinyin):songxiaofeng
- Date of Birth:1972-12-26
- School/Department:化学工程学院
- Administrative Position:系主任
- Education Level:Postgraduate (Postdoctoral)
- Business Address:化工楼6226
- Contact Information:13080037022（微信）/QQ:15359494615
- Degree:Doctoral Degree in Science
- Alma Mater:吉林大学
- Teacher College:化学工程学院
- Discipline:Polymer Chemistry and Physics
Applied Chemistry
Contact Information
No content
- Paper Publications
Hydroxyapatite cross-linked in situ polyvinyl alcohol hydrogel for bionic calcified cartilage layer
Release time:2023-12-18 Hits:
- Affiliation of Author(s):化学工程学院
- Journal:Colloids and Surfaces B: Biointerfaces
- Funded by:省、市、自治区科技项目
- Key Words:composite hydrogel
- Abstract:Many tissue engineering constructs have been investigated for repairing the calcified cartilage layer in the recent years, but engineering a consistent and stable interface to facilitate a graft-to-bone fixation remains a concern. In the work, hydroxyapatite (HA) is modified by diisocyanate (HDI) and integrated with polyvinyl alcohol (PVA) to prepare the hydrogel. The IR shows that HDI is grafted onto HA and helps HA to cross-link in situ in the PVA gel network. When the mass ratio of HA/PVA is 3.5 wt%, the swelling rate in the PBS of different pH reduced with time prolong, and the hydrogel takes on good swelling resistance. The tensile strength and toughness are 1890 KPa and 264 KJ/m-3, respectively, while the compression strength reaches 1125 KPa at compressive strain of 60%. The hydrogel not only is well durable via continuous 100 rounds of compression-recovery, but also has excellent bioactivity. The work will provide a platform for developing multifunctional soft tissue scaffold.
- Co-author:曲瑞,宋晓峰
- First Author:songxiaofeng
- Indexed by:Journal paper
- Volume:230
- Page Number:1
- Translation or Not:no
- Date of Publication:2023-08-07