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Affiliation of Author(s):化学工程学院
Teaching and Research Group:化学工程学院
Journal:Research on CHEMICAL INTERMEDIATES
Funded by:自选课题
Key Words:Pyridobenzodiazepines Cyclization PPA Catalyst Bischler–Napeiralski reaction
Abstract:A new one-pot Bischler–Napeiralski type cyclization reaction between pyridine-1,2-diamines and various carboxylic acids with PPA as catalyst to prepare pyridobenzodiazepines is proposed. In the new synthetic route, the reaction time is only one-third of the methods reported. The synthetic strategy provides an efficient way to prepare novel structurally diversified heterocyclic compounds of pyridobenzodiazepine family with potential pharmaceutical or biological activities.
First Author:shifuqiang
Indexed by:Journal paper
Volume:36
Issue:3
Page Number:1
Number of Words:1
ISSN No.:ISSN 0922-6168
Translation or Not:no
Date of Publication:2010-03-12