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Affiliation of Author(s):化学与生命科学学院

Teaching and Research Group:化学教研室

Journal:Analytical Methods

Funded by:省、市、自治区科技项目

Abstract:The abnormal level of Cu2+ or GSH can cause variety of neurodegenerative diseases in humans. Thus, the selective and sensitive detection of Cu2+ and GSH has inspired intensive research efforts in biological sample analysis fields. Herein, an “on–off–on” fluorescent probe based on nitrogen and sulfur co-doped carbon dots (N,S-CDs) has been successfully prepared for the detection of Cu2+ and GSH. The “turn-off” process of fluorescence in the presence of Cu2+ ions was induced by forming a non-luminescent ground state complex due to the interaction between surface groups of the probe and Cu2+ ions. Moreover, the strong coordination between GSH and Cu2+ could destroy the structure of the complex and restore the fluorescence to “turn-on”. This fluorescent probe had excellent selectivity and high sensitivity toward Cu2+ and GSH with the limits of detection (LODs) of 38 nM and 41 nM. More importantly, the as-prepared N,S-CDs served as an efficient fluorescent probe for not only detecting Cu2+ ions in lake water and tap water, and GSH in BSA solution, but also sensing Cu2+ and GSH in living cells. Therefore, these N,S-CDs could be considered as a promising fluorescence probe candidate for environmental monitoring and biological imaging.

First Author:jiangchunzhu

Indexed by:Journal paper

Volume:12

Page Number:1

Translation or Not:no

Date of Publication:2020-10-05

Pre One:【SCI2区通讯作者姜春竹】Surface state dominated and carbon core coordinated red-emitting carbon dots for the detection of Cr2O72- and cell imaging Next One:【SCI通讯】A sensitive “ON–OFF” fluorescent probe based on carbon dots for Fe2+ detection and cell imaging